(trademark) a liquid that temporarily disables a person; prepared as an aerosol and sprayed in the face, it irritates the eyes and causes dizziness and immobilization
Hint 2clue words
Self: (used as a combining form) relating to--of or by or to or from or for--the self
Defense: (military) military action or resources protecting a country against potential enemies
What is the 4-letter answer to "Self-defense spray" crossword clue?
The answer to the "Self-defense spray" crossword clue is MACE. This answer contains 4 letters and was confirmed in the Daily Themed puzzle.
Which crossword used "Self-defense spray" clue?
This crossword clue most recently appeared in the Daily Themed puzzle on August 23, 2025. Daily crossword puzzles often reuse popular clues, so this clue may appear again in future puzzles from the same publication or others.
What is the meaning of MACE?
The word MACE means: (trademark) a liquid that temporarily disables a person; prepared as an aerosol and sprayed in the face, it irritates the eyes and causes dizziness and immobilization. This definition provides context for why it fits the crossword clue "Self-defense spray".